A victory at Anfield would see the Reds end in the Champions League places for only the second time in the past eight seasons.
It would also result in a total of 76 points - a haul only bettered twice in the last 10 terms.
“I don’t think we need different kinds of descriptions for this game, so it’s a ‘cup final’ or a ‘World Cup final’ or that it’s the most important game of however many years and everything,” Klopp told the club's official website.
“It is a football game. If we really—and I know we do—expected from ourselves that in each game we win the game, what is the difference?"
Roberto Firmino sat out the 4-0 win at West Ham with a muscle niggle and has had his load managed in training this week.
Klopp: Bayern wouldn't dominate PL
It is hoped that will be fit enough to feature in the matchday squad.
“Very positive," Klopp said on the Brazilian's prognosis.
“We could not decide until now, but he feels good and he feels comfortable. He did a lot of things, but was not part of team training. That’s not a problem after this long season.
“I think we will make a final test tomorrow. In this moment, I would rather say ‘yes’ than ‘perhaps’, but I am not sure.”
Captain Jordan Henderson continues to be sidelined with a foot problem.
Neither side have any suspension concerns to worry about.
LIVERPOOL POTENTIAL STARTING LINE-UP
Klopp should keep faith with the XI that demolished the Hammers last weekend barring any new enforced absences.
If Firmino is sharp enough to start, however, he could be an option to replace Divock Origi and work in tandem with Daniel Sturridge.
MIDDLESBROUGH TEAM NEWS
Boro will end the season with their fewest wins in a Premier League campaign. They've recorded just five so far, with their previous lowest the seven amassed in 2008/09.
They have attempted the fewest shots in total (342) and shots on target (97) this term.
However, the Reds boss has warned the result in Sunday's encounter is not a foregone conclusion.
"We play Middlesbrough and it will be difficult. They have nothing to lose while we have everything to win," Klopp highlighted following the victory at London Stadium.
"I said in the dressing room immediately after, that we've known for weeks that we will have to go until the end, so that's no problem for us.
"We want to do this, we want to be successful. If we win, we deserve to be in the Champions League, if not, then we don't deserve it. That's pretty easy.
Victor Valdes (rib) and Gaston Ramirez (pelvis) remain sidelined for the visitors.
Defender Daniel Ayala could return to the squad after shaking off an ankle injury.
BEST OPTA MATCH FACTS
Middlesbrough are one of three teams to visit Anfield on 10+ occasions in the Premier League without leaving with all three points (Sunderland – 16, Middlesbrough – 14 and Bolton – 13).
The Reds have won each of their last four Premier League contests against Middlesbrough at Anfield, scoring 2+ goals on each occasion.
Liverpool have won eight of their 10 Premier League final day games at Anfield (D2), scoring 27 goals.
TV COVERAGE & KICK-OFF TIME
Kick off is at 3pm BST and the match will be televised live on Sky Sports.