There are just four games left to play in the league and Massimiliano Allegri's men cannot afford to slip up, particularly now that the momentum is behind Maurizio Sarri's side.
Inter are out of the title race, but the Nerazzurri can still secure Champions League football and a win over Juve could see them move up to third.
|Game||Inter vs Juventus|
|Date||Saturday, April 28|
|Time||19:45 BST / 14:45 ET|
|Stream (US only)||fubo TV (7-day free trial)|
TV Channel, Live Stream & How To Watch
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial).
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
|beIN Sports||fubo TV (7-day free trial)|
In the United Kingdom (UK), the game can be watched live on TV on BT Sport 2 and it can be streamed live online using the BT Sport app.
|UK TV channel||Online stream|
|BT Sport 2||BT Sport app|
Squads & Team News
|Goalkeepers||Buffon, Pinsoglio, Szczesny|
|Defenders||Benatia, Sandro, Howedes, Barzagli, Rugani, Lichtsteiner|
|Midfielders||Pjanic, Khedira, Marchisio, Matuidi, Asamoah, Bentancur|
|Forwards||Cuadrado, Higuain, Dybala, Costa, Mandzukic, Bernardeschi|
Juve will be without centre-back Giorgio Chiellini, who suffered a knee injury last week, while Mattia De Sciglio has not been included in the match panel.
Potential Juventus starting XI: Buffon; Lichtsteiner, Sandro, Benatia, Barzagli; Khedira, Pjanic, Matuidi; Costa, Dybala, Higuain.
|Goalkeepers||Handanovic, Padelli, Berni|
|Defenders||Lopez, Cancelo, Ranocchia, Santon, Miranda, Dalbert, D'Ambrosio, Skrinkiar|
|Midfielders||Rafinha, Valero, Brozovic, Vecino|
|Forwards||Icardi, Karamoh, Eder, Perisic, Candreva, Pinamonti|
There is no place in the squad for Roberto Gagliardini, who is out of action due to a hamstring injury.
Potential Inter starting XI: Handanovic; Cancelo, Miranda, Skriniar, Santon; Rafinha, Brozovic, Valero, Candreva, Perisic, Icardi.
Betting & Match Odds
Juventus are favourites to win with dabblebet offering odds of 8/5 on the Bianconeri. Inter are priced at 2/1 to win and a draw is available at 21/10.
After witnessing his side's last-minute capitulation against Napoli last week, Allegri believes that the clash against Inter has now become a "decisive" game in their pursuit of the Scudetto.
"We are still top of the table, we still have the advantage," the Juve boss told reporters. "There are four games to go, two at home and two away, so we'll see what happens."
The two teams could not be separated when they met in Turin back in December, playing out a 0-0 draw, and Saturday's encounter is likely to be similarly tight.
However, with talent such as Mauro Icardi on one side and Paulo Dybala on the other - the pair have 47 league strikes between them - on the pitch there is certainly plenty of potential for goals.