Alvaro Morata starts after missing the last game with a minor injury while Willian, Pedro, Davide Zappacosta, Andreas Christensen and Willy Caballero also come in as Antonio Conte makes six changes from the team that beat Liverpool.
Thibaut Courtois has a back injury which sees third choice goalkeeper Eduardo promoted to the bench to act as back-up for Caballero.
Huddersfield bring in Philip Biling, Rajiv van La Parra and Laurent Depoitre after their impressive away draw with Manchester City at the weekend.
Chelsea: Caballero; Azpilicueta, Christensen, Rudiger; Zappacosta, Kante, Fabregas, Alonso; Willian, Morata, Pedro.
Subs: Eduardo, Cahill, Moses, Bakayoko, Barkley, Hazard, Giroud.
Huddersfield: Lossl, Smith, Kongolo, Zanka, Schindler, Lowe, Hogg, Mooy, Billing, Van La Parra, Depoitre
Subs: Coleman, Malone, Pritchard, Ince, Quaner, Mounie, Hadergjonaj.