The two London sides face each other with new managers, with Unai Emery and Maurizio Sarri on the touchline ahead of their first terms managing in the Premier League.
Here is everything you need to know ahead of Wednesday's fixture.
|Game||Arsenal vs Chelsea|
|Date||Wednesday, Aug 1|
|Time||7:05pm BST / 2:05pm ET|
TV Channel, Live Stream & How To Watch
In the United States (US) the game will be shown live on television on both ESPN 2 and the Spanish language equivalent, ESPN Deportes. It can also be streamed live online using ESPN+.
|US TV channel||Online stream|
In the United Kingdom (UK), the game can be watched live on Premier Sports and online via the Premier Player.
|UK TV channel||Online stream|
|Premier Sports||Premier Player|
Squads & Team News
|Goalkeepers||Cech, Leno, Martinez|
|Defenders||Bellerin, Kolasinac, Chambers, Holding, Mustafi, Papastathopoulos, Mavropanos, Maitland-Niles, Osei-Tutu|
|Midfielders||Elneny, Guendouzi, Smith Rowe, Willock, Ramsey, Mkhitaryan, Ozil|
|Forwards||Nelson, Iwobi, Nketiah, Perez, Lacazette, Aubameyang|
Arsenal essentially have their full-strength squad on hand apart from Lucas Torreira and Danny Welbeck, who are the only two players still enjoying their post-World Cup holiday following their duties with Uruguay and England.
New signing Torreira, however, has already flown to London and could be in line to join the squad in Dublin.
Potential Arsenal XI: Leno; Bellerin, Papastathopoulos, Mustafi, Kolasinac; Ramsey, Smith Rowe, Mkhitaryan; Ozil, Lacazette, Aubameyang.
|Goalkeepers||Bulka, Thompson, Collins|
|Defenders||Luiz, Ampadu, Tomori, Hector, Kalas, Alonso, Emerson, Zappacosta|
|Midfielders||Aina, Fabregas, Drinkwater, Bakayoko, Barkley, Pasalic, Jorginho, Palmeri|
|Forwards||Pedro, Piazon, Musonda, Hudson-Odo, Morata, Abraham|
Kurt Zouma is the only injury concern for Chelsea, and has been ruled out of the pre-season tour.
Willian will be unable to join up with the Blues on their pre-season duties due to visa issues.
Potential Russia XI: Caballero; Azpilicueta, Rudiger, Luiz, Alonso; Fabregas, Jorginho, Bakayoko; Pedro, Morata, Hudson-Odoi.
Betting & Match Odds
Arsenal are priced 13/10 to win the tie according to dabblebet, while a draw is available for 5/2. Odds of Chelsea winning are up at 9/5.
Sarri's first season in charge of the Blues will undoubtedly require him to return the squad to the Champions League at the very minimum. Former manager Antonio Conte was dismissed for placing Chelsea in fifth spot, despite winning the league in his first term and winning the FA Cup in his second.
The West London side won 1-0 against Perth Glory in Sarri's first game in charge of the club but only managed to register victory over Inter in the next game by way of penalties. His recoup of midfielder Jorginho, who followed him from Napoli, shows his intention of implementing his famed 'Sarriball' to the FA Cup champions – though Sarri will need more time to have his squad fully understand the philosophy.
Stars such as Eden Hazard and Thibaut Courtois are still enjoying their post-World Cup holidays after spearheading Belgium to a third-placed finish in Russia, though the two are still the subject of rumoured transfer interest from the likes of Real Madrid.
Arsenal, on the other hand, are also set to embark on a new era under ex-PSG manager Emery and are readying for their first ever season competing in the Premier League without long-term manager Arsene Wenger.
The Gunners will be strengthened by the attacking likes of Pierre-Emerick Aubameyang and Alexandre Lacazette, who had the entire summer off, while Mesut Ozil has also returned to the fold following his abrupt retirement from German national team duty.
The North Londoners finished in sixth place in the Premier League and will also be aiming to return to the Champions League.