Mendy was barely tested in Sunday's encounter, however, he was beaten by Equatorial Guinea's first shot on target in the 57th minute.
With no significant contribution, the Bayern Munich right-back was found wanting when it mattered.
Ciss played a major role in the build-up to the third goal. It started with his fine control then his run into the box before cutting back to set up Sarr to score.
Another solid performance from the captain and he was lucky to have a penalty call against him ruled out after the restart.
The 25-year-old continued his fine partnership with Koulibaly and it helped limit the attacking threats of Equatorial Guinea.
The Leicester City midfielder pulled the strings in the middle of the park which contributed to Senegal's dominance.
His performance earned him the Man of the Match award.
The midfield general shielded the defence with crucial tackles on several occasions.
Received a yellow card in the 18th minute and he made no significant impact before his replacement after the hour-mark.
The Villarreal forward continues his goal drought in the tournament. On Sunday, Dia lacked the spice to add flavour to the Teranga Lions' attack.
His work rate and runs constantly unsettled the National Thunder defence, though he had no shot on target in the game.
Mane played in a lovely through ball in the 28th minute that led to the opening goal.
The Alanyaspor star scored his first goal in Cameroon by finishing off Mane's assist and his presence upfront kept the Equatorial Guinea defenders on their toes.
The Watford player was introduced in the 57th minute for his first game since he suffered a knee injury on November 20.
He was well-positioned to secure Senegal's progress into the semis with his 79th-minute strike.
The combative midfielder was introduced in the 64th minute and he produced a super-sub moment as his first touch went straight into the back of the net.
Kouyate was at alert to take advantage of a defensive mix-up and put the Teranga Lions ahead again in the 67th minute.
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