After failing to proceed in the Champions league, Tusker will start their Confederation Cup journey with a home game against the Tunisian side at the Nyayo Stadium on Sunday.
Despite criticism that came his way after the 3-0 loss to Kariobangi Sharks, Bwire has started ahead of Emery Mvuyekure and Patrick Matasi as Tusker - who have struggled on the domestic front - hope for a better outing.
The former Kakamega Homeboyz full-back has been given a starting nod ahead of Kevin Monyi.
Wandera's experience and composure is key in the game against Sfaxien as the Kenyan league champions hope to have a successful campaign in Caf's second-tier club competition.
The Tanzanian has been a reliable star at the heart of Tusker's defence since he signed at the beginning of the season and has kept his place once again in the starting XI.
The Harambee Star will work closely with Kirenge as they hope to keep the visitors at bay in the first-leg meeting.
Although he mostly operated as a centre-back at AFC Leopards, Matano has always preferred to have Senaji as his holding midfielder and the case has not changed as they host Sfaxien.
Macharia will operate just in front of Senaji and his experience and ability to frustrate the opponents, especially with his clinical tackles will be key for the Brewers should he be on top of his game.
Tusker's designated free-kick taker and his speed and creativity may end up hurting Sfaxien and hand the home side an added advantage.
The Tanzanian has scored goals for Tusker in both local and continental games and he carries a huge responsibility of ensuring he gets more against the play-offs rivals.
Since he signed for Tusker, Kibwana has regularly kept a starting position and this game gives him another opportunity to show the technical bench why he deserves to be a first-teamer.
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