Manchester United team news
Anthony Martial is set for his return from a hip problem and could replace the below-par Wout Weghorst in the XI.
Raphael Varane, Marcus Rashford, Marcel Sabitzer are also in contention after recovering from their knocks. However, Alejandro Garnacho, Tom Heaton, Christian Eriksen and Donny van de Beek all remain sidelined with injuries.
Casemiro will miss another game after this one amid his four-match domestic ban.
Meanwhile, right-back Aaron Wan-Bissaka is expected to be available for selection after missing Sunday's game due to illness.
Manchester United possible XI: De Gea; Wan-Bissaka, Varane, Martinez, Malacia; Sabitzer, Fred; Sancho, Fernandes, Rashford; Martial
|Goalkeepers||De Gea, Butland|
|Defenders||Martinez, Varane, Maguire, Lindelof, Jones, Shaw, Malacia, Williams, Dalot, Wan-Bissaka|
|Midfielders||McTominay, Sabitzer, Fred, Fernandes, Pellistri|
|Forwards||Rashford, Elanga, Antony, Sancho, Martial, Weghorst|
Brentford team news
Midfielder Shandon Baptiste returns after serving his one-game ban, but Vitaly Janelt remains sidelined with Kristoffer Ajer and Keane Lewis-Potter.
Pontus Jansson is set to keep his place after scoring on his first Premier League start since October 2022, while an expected change in attack should see Yoane Wissa start in place of Mikkel Damsgaard.
Brentford possible XI: Raya; Mee, Pinnock, Jansson; Hickey, Jensen, Norgaard, Henry; Mbeumo, Toney, Wissa
|Goalkeepers||Raya, Strakosha, Cox|
|Defenders||Pinnock, Jansson, Mee, Zanka, Henry, Hickey, Roerslev, Stevens|
|Midfielders||Norgaard, Jensen, Dasilva, Onyeka, Baptiste, Ghoddos, Damsgaard|
|Forwards||Toney, Schade, Wissa, Mbeumo|
|August 13, 2022||Brentford 4-0 Manchester United||Premier League|
|May 3, 2022||Manchester United 3-0 Brentford||Premier League|
|January 20, 2022||Manchester United 1-3 Brentford||Premier League|
|July 29, 2021||Manchester United 2-2 Brentford||Club friendly|
|April 12, 1947||Brentford 0-0 Manchester United||Premier League|