Ghana made a trip to Spain on Sunday for an international friendly game against Nicaragua at Francisco Artes Carrasco on Tuesday.
The Black Stars fell 3-0 against the South America heavyweights Brazil in another friendly played on Friday in France.
Coach Otto Addo is expected to play with three centre-backs against Nicaragua owing to players at his disposal.
Mohammed Salisu, Tariq Lamptey and Inaki Williams - who switched their allegiance recently, might make their full debuts as well.
GOAL predicts how the Black Stars might start.
Despite conceding three in the loss against Brazil, the Charlton Athletic stopper still has Addo's backing and is expected to start ahead of Richard Ofori.
The Southampton defender might make his full debut for the Black Stars in a three-man defence comprising of Leicester City's Daniel Amartey and Strasbourg's Alex Djiku.
The bulky 27-year-old has already featured 11 times for the national team this year and is definitely among the first names on the starting sheet.
Djiku was one of the better players against Brazil and his presence at the back - alongside Salisu and Amartey, will further strengthen the Black Stars' defence.
The Brighton & Hove Albion player has featured five times at club level so far this season and was involved as a substitute against the Samba Boys.
After impressing in the few minutes he was on the pitch, the youngster might be rewarded with a start on Tuesday.
He has already made three appearances for Championship side Reading this season. His energy on the left is just on another level and might make a second appearance for the Black Stars this year after showing his worth in the tough Brazil match.
Baba was thrown into the deep end on Friday after Thomas Partey pulled out of the team owing to a suspected injury.
The RCD Mallorca man will be required to provide cover in defence and help keep the shape in midfield.
Kudus has been exceptional at Ajax in recent weeks it explains why he has made seven appearances already for the Eredivisie outfit this season.
The midfielder did not have the desired impact against the well-oiled Brazil team and is keen to make amends on Tuesday if given a chance.
The skipper struggled in the loss against the Selecao and will be aiming at redeeming himself.
The 32-year-old will be playing behind his brother Jordan Ayew and Inaki Williams, who might lead the line.
The Crystal Palace attacker has not yet opened his account for the Eagles this season and despite failing to have a major impact on Friday, Addo might give him another opportunity.
Williams switched allegiance a couple of weeks ago and after getting a few minutes against Brazil, he might start alongside Jordan Ayew hoping to get his first goal for the Black Stars.
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